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. 2019 Oct 10;9:14613. doi: 10.1038/s41598-019-50882-x

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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(A) There was no significant difference in fibronectin levels in each group. (B) The expression of MMP9 was enhanced in the cHA group. (C) MMP3, and 9 levels were both up-regulated in the cHA groups compared with the non-cHA treated groups.