Table 1.
Anti-acne agent Bacteria |
antibiotics | non-antibiotics | |||||||
---|---|---|---|---|---|---|---|---|---|
Vancomycin | Tetracycline | Erythromycin | Oxacillin | Clindamycin | Dapsone | Salicylic acid | Azelaic acid | Benzoyl peroxide 75% | |
P. acnes ATCC 6919 |
0.25–1 | 0.125–1 | 0.25 | 0.25–1 | 0.125 | 4100 | 4000–8000 | 4000–8000 | 1024–>2048 |
A. acidipropionici ATCC 25562 |
0.125 | 0.5 | 0.25–4 | 0.25–1 | 0.03–0.125 | 1025–>4100 | 500–8000 | 4000–16000 | 1024–>2048 |
C. granulosum ATCC 25564 |
0.25 | 0.25 | 0.125–2 | 0.25–4 | 0.03–0.25 | 512–>4100 | 2000–8000 | 4000–8000 | 1024–>2048 |
S. aureus, MRSA ATCC 43300 |
1 | 0.25 | >32 | 8–64 | >32 | >4100 | 4000–8000 | 2000–8000 | 2048–>2048 |
[n = 4, duplicate results from 2 independent assays.]