Skip to main content
. 2019 Oct 10;9:14664. doi: 10.1038/s41598-019-51140-w

Figure 2.

Figure 2

Enzyme-linked immunosorbent assay analysis of TNF-α and IL-1β expression 7 days after CCI. The production of TNF-α (A) and IL-1β (B) in the spinal cord at day 7 after CCI was determined by ELISA. CCI caused a significant increase in TNF-α and IL-1β expression. Ghrelin significantly inhibited TNF-α and IL-1β expression compared to the CCI group (A: p < 0.01, n = 5, t = 11.81, df = 8; B: p < 0.01, n = 5, t = 10.32, df = 8), while TNF-α and IL-1β expression levels were similar between the sham group and the sham plus ghrelin group (A: p < 0.01, n = 5, t = 7.442, df = 8; B: p < 0.01, n = 5, t = 5.729, df = 8). Results are presented as mean ± SD. n = 5. ##p < 0.01 vs Sham group; $$p < 0.01 vs CCI group.