. 2019 Oct 10;9:14656. doi: 10.1038/s41598-019-51084-1

Table 1.

Mean survival time of tg338 reporter mice inoculated with spleen material from tg338 mice infected with L-BSE or C-BSE.

tissue	Dilution	L-BSE		C-BSE
tissue	Dilution	n/n0	Mean survival time* (days ± sem)	n/n0	Mean survival time* (days ± sem)
spleen	1/1	6/6	144 ± 2^‡	4/4	229 ± 4^§
	1/1	6/6	142 ± 2^‡	6/6	138 ± 1
	10-4	6/6	na	6/6	176 ± 3
brain	10-5	6/6	261 ± 16	6/6	217 ± 9^§
	10-6	6/6	281; 307	2/6	286;534
	10-7	0/6	>660	0/6	>660

^*Mean survival time of tg338 reporter mice inoculated with spleen material from tg338 infected with L-BSE or C-BSE.

^‡,§For pair comparison: this indicates that spleens of L-BSE infected animal are 1000 to 10000-fold more infectious than those of C-BSE infected animals. The symbols indicate inoculum dilution factors for which the incubation times (i.e. the inoculum concentration) are similar.