Fig. 5.

Effects of EB on UVB-induced MAPK signaling activation. HaCaTs were irradiated with UVB (125 mJ/cm²), followed by treatment with EB (1, 10, and 100 µg/mL) for 0.5 h. Phosphorylated and non-phosphorylated forms of ERK, JNK and P38 were detected by Western blot (a). The band intensities were quantified by densitometry, normalized to the level of β-actin, and calculated as the percentage of the basal response (b–d). The results were shown as the mean ± SD of three independent experiments. ^##P < 0.01, ^###P < 0.001, compared to the Basal; **P < 0.01, ***P < 0.001, compared to the UVB irradiated cells