Table 2.
Frequency distribution of genotypes for ADH1B and ALDH2
| A. Symptomatic group vs asymptomatic group | |||
|---|---|---|---|
| Variables | Symptomatic group (n = 90) | Asymptomatic group (n = 108) | P‐value |
| ADH1B gene | |||
| ADH1B Arg/Arg, n (%) | 7 (7.8) | 5 (4.6) | .355 |
| ADH1B Arg/His, n (%) | 33 (36.7) | 45 (41.7) | .473 |
| ADH1B His/His, n (%) | 50 (55.6) | 58 (53.7) | .794 |
| ALDH2 gene | |||
| ALDH2 Glu/Glu, n (%) | 56 (62.2) | 59 (54.6) | .281 |
| ALDH2 Glu/Lys, n (%) | 26 (28.9) | 42 (38.9) | .140 |
| ALDH2 Lys/Lys, n (%) | 8 (8.9) | 7 (6.5) | .524 |
| B. Alcohol‐related group vs alcohol‐unrelated group | |||
|---|---|---|---|
| Variables | Alcohol‐related group (n = 16) | Alcohol‐unrelated group (n = 74) | P‐value |
| ADH1B gene | |||
| ADH1B Arg/Arg or ADH1B Arg/His, n (%) | 3 (18.8) | 37 (50.0) | .023 |
| ADH1B His/His, n (%) | 13 (81.2) | 37 (50.0) | |
| ALDH2 gene | |||
| ALDH2 Glu/Glu, n (%) | 10 (62.5) | 46 (62.2) | .980 |
| ALDH2 Glu/Lys, n (%) | 5 (31.3) | 21 (28.4) | .818 |
| ALDH2 Lys/Lys, n (%) | 1 (6.3) | 7 (9.5) | .683 |
Data are expressed as number (%).