Table 3.
Concordance and agreement for AQP4 antibody assays.
| Assay | T-IIF | ELISA | EI M1/M23 | EI AQP4 |
|---|---|---|---|---|
| ELISA | 121/141 (86) | |||
| 0.556 | n/a | |||
| <0.001 | ||||
| EI M1/M23 | 131/141 (93) | 121/141 (86) | ||
| 0.790 | 0.605 | n/a | ||
| <0.001 | <0.001 | |||
| EI AQP4 | 132/141 (94) | 122/141 (87) | 136/141 (96) | |
| 0.808 | 0.620 | 0.904 | n/a | |
| <0.001 | <0.001 | <0.001 | ||
| Ox AQP4 | 134/141 (95) | 122/141 (87) | 136/141 (96) | 139/141 (99) |
| 0.847 | 0.612 | 0.902 | 0.960 | |
| <0.001 | <0.001 | <0.001 | <0.001 |
All data presented as: Concordance n/N (%); bold values represent the Cohen's kappa coefficient; italic value represent the P-value; n/a, not applicable.
T-IIF, tissue-based indirect immunofluorescence; ELISA, enzyme linked immunosorbent assay; EI M1/M23, Euroummun® M1/M23 biochip slide; EI-CBA, Euroimmun® AQP4 fixed cell-based assay; Ox-CBA, Oxford AQP4 live cell-based assay.