Table 4.
Univariate and multivariate cox regression for predicting mortality.
| Univariate | Multivariate | |||||
|---|---|---|---|---|---|---|
| HR | 95% CI | p-value | HR | 95% CI | p-value | |
| Age | 1.05 | 1.014–1.091 | 0.006 | 1.058 | 0.966–1.063 | 0.58 |
| Sex (male) | 2.78 | 1.02–7.58 | 0.02 | 2.13 | 0.4–11.43 | 0.38 |
| Hypertension | 1.64 | 0.78–3.42 | 0.19 | |||
| Diabetes mellitus | 1.48 | 0.7–3.1 | 0.3 | |||
| MELD | 1.111 | 1.05–1.18 | 0.001 | 1.2 | 1.07–1.36 | 0.002 |
| CRP | 1.01 | 1.003–1.025 | 0.013 | 1.01 | 0.999–1.02 | 0.06 |
| UPCR | 1.04 | 0.84–1.31 | 0.69 | |||
| FENa | 0.87 | 0.55–1.35 | 0.523 | |||
| Cystatin C | 5 | 1.9–13.2 | 0.001 | |||
| Corrected NGAL | 1.001 | 0.999–1.002 | 0.27 | |||
| [TIMP2][IGFBP7]/1000 | 1.04 | 0.638–1.702 | 0.87 | |||
| MELD-cystatin C | 1.093 | 1.043–1.146 | <0.001 | 1.1 | 1.018–1.146 | 0.001 |
Multivariate regression included Age, sex, HTN, DM, CKD, CRP and MELD or MELD using biomarker.
NGAL: neutrophil gelatinase associated lipocalin, TIMP-2: tissue inhibitor of metalloproteinase-2, IGFBP7: insulin-like growth factor-binding protein7.