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. 2019 Oct 10;9:14503. doi: 10.1038/s41598-019-51021-2

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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A comparison of the fucosylated AGP level between before and after administration of nivolumab. The fAGP level in each patient (n = 39) was measured before and after starting the administration of nivolumab. Accordingly, the fAGP level was measured at baseline and at 1 month in most of the patients and at 3 (No. 36) and 6 month (Nos 34, 38 and 39). The former was commonly indicated with a black-colored bar, and the latter was with differently-colored bars grouped according to the classification of the RECIST criteria²⁸ conducted at the moment; PD (red), SD (yellow) and PR (blue), respectively. The solid line at 16.67 U/μg indicates the cut-off value. A gray-colored screen indicates patients who were alive during the observation time (see the details in Text).