TABLE 1.
Mice for lung histology (lung injury score) | Mice for BAL analysis (white cells, TNFα, MIP-2, proteins, BAL quantitative bacteriology after live CoNS tracheal inoculation) | Mice for quantitative lung tissue bacteriology | ||
Eighteen groups of mice sacrificed at H36 n = 178 | ||||
PBS | 6 | 13 | 13 | |
CoNS 106 | Inactivated | 6 | 6 | – |
Live | 6 | 17 | 9 | |
CoNS 107 | Inactivated | 6 | 7 | – |
Live | 6 | 28 | 10 | |
CoNS 108 | Inactivated | 6 | 6 | – |
Live | 6 | 17 | 10 | |
Eight groups of mice sacrificed at H12 n = 43 | ||||
PBS | 6 | 5 | – | |
CoNS 106 | Live | 5 | 6 | – |
CoNS 107 | Live | 5 | 5 | – |
CoNS 108 | Live | 6 | 5 | – |
PBS, phosphate-buffered saline; BAL, bronchoalveolar lavage; CoNS, inoculation of coagulase negative Staphylococcus haemolyticus, whose inoculum is expressed in colony forming units; H36 = 36 h; H12 = 12 h.