Figure 6.

The combination of TFDG and a β‐lactam antibiotic protects mice from BAA1717 pneumonia. A, The combination of TFDG and a β‐lactam antibiotic protects infected mice from BAA1717 mortality. Kaplan‐Meier survival estimates were used for the mortality rate at 72 h. B, Pathological observation by naked eye and (C) light microscopy. D, The combination influences the colonization of BAA1717 in the lungs. E, The influence of the combination on the lung wet/dry weight ratio in BAA1717‐infected mice. Data are expressed as the means ± SD of three independent experiments. (* indicates P < .05 and ** indicates P < .01 compared with the control group; two‐tailed Student's test)