Table 2.
Genotype and allele frequency distributions for FokI, BsmI, ApaI, and TaqI polymorphisms in leprosy per se, PB, and MB clinical forms patients and controls.
| Leprosy per se | PB | MB | Controls | |
|---|---|---|---|---|
| N = 404 | N = 86 | N = 310 | N = 432 | |
| Genotype and alleles | n (%) | n (%) | n (%) | n (%) |
| FokI (rs2228570) | ||||
| F/F | 176 (43.6) | 42 (48.8) | 127 (41) | 191 (44.2) |
| F/f | 168 (41.6) | 32 (37.2) | 135 (43.5) | 195 (45.1) |
| f/f | 60 (14.8) | 12 (13.9) | 48 (15.5) | 46 (10.7) |
| F | 520 (64.4) | 116 (67.0) | 389 (63.0) | 577 (66.8) |
| f | 288 (35.6) | 56 (33.0) | 231 (37.0) | 287 (33.2) |
| BsmI (rs1544410) | ||||
| B/B | 57 (14.1) | 12 (13.9) | 44 (14.2) | 52 (12.0) |
| B/b | 199 (49.3) | 44 (51.2) | 153 (49.4) | 202 (46.8) |
| b/b | 148 (36.6) | 30 (34.9) | 113 (36.5) | 178 (41.2) |
| B | 313 (38.7) | 68 (40.0) | 241 (39.0) | 306 (35.4) |
| b | 495 (61.3) | 104 (60.0) | 379 (61.0) | 558 (64.6) |
| ApaI (rs7975232) | ||||
| A/A | 129 (31.9) | 30 (34.9) | 97 (31.3) | 131 (30.3) |
| A/a | 199 (49.3) | 43 (50) | 151 (48.7) | 214 (49.5) |
| a/a | 76 (18.8) | 13 (15.1) | 62 (20.0) | 87 (20.1) |
| A | 457 (56.6) | 103 (60.0) | 345 (56.0) | 476 (55.1) |
| a | 351 (43.4) | 69 (40.0) | 275 (44.0) | 388 (44.9) |
| TaqI (rs731236) | ||||
| T/T | 153 (37.9) | 32 (37.2) | 115 (37.1) | 184 (42.6) |
| T/t | 203 (50.2) | 44 (51.2) | 158 (51) | 198 (45.8) |
| t/t | 48 (11.9) | 10 (11.6) | 37 (11.9) | 50 (11.6) |
| T | 509 (63.0) | 108 (63.0) | 388 (63.0) | 566 (65.5) |
| t | 299 (37.0) | 64 (37.0) | 232 (37.0) | 298 (34.5) |
PB, Paucibacillary; MB, Multibacillary; N, population size; n, number of individuals; %, percentage.