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. 2019 Oct 4;9:1002. doi: 10.3389/fonc.2019.01002

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Copyright © 2019 Cui.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Schematic representation of T_H22/IL-22's role in CRC pathogenesis. Evidence obtained from most studies has suggested that T_H22/IL-22 promotes the development of CRC through diverse pathways.