Summary of findings for the main comparison. Hyperbaric oxygen (HBO) versus no HBO.
| Hyperbaric oxygen (HBO) versus no HBO | ||||||
|
Patient or population: people requiring dental implants Settings: specialist centre Intervention: HBO Comparison: no HBO | ||||||
| Outcomes | Illustrative comparative risks* (95% CI) | Relative effect (95% CI) | Number of participants (studies) | Quality of the evidence (GRADE) | Comments | |
| Assumed risk | Corresponding risk | |||||
| Without HBO | HBO | |||||
| Prosthetic failure | Low risk population | RR 3.00 (0.13, 67.06) | 24 (1) | ⊕⊝⊝⊝2 very low quality | ||
| 10 per 10001 | 30 per 1000 (1 to 670) | |||||
| High risk population | ||||||
| 100 per 1000 | 300 per 1000 (13 to 1000) | |||||
| *The basis for the assumed risk (e.g. the median control group risk across studies) is provided in footnotes. The corresponding risk (and its 95% CI) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI). | ||||||
1The risk in the control arm was 0% so low risk of 1% and high risk of 10% assumed. 2 Downgraded due to one small study at high risk of bias.
CI = confidence interval; RR = risk ratio.
GRADE Working Group grades of evidence. High quality (⊕⊕⊕⊕): further research is very unlikely to change our confidence in the estimate of effect. Moderate quality (⊕⊕⊕⊝): further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate. Low quality (⊕⊕⊝⊝): further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate. Very low quality (⊕⊝⊝⊝): we are very uncertain about the estimate.