Table I.
Differentially expressed proteins in SCC12 cellsa.
| Spot# | Protein name | Accession no. | MW (kDa)/pI | No. of matched peptides | Seq. coverage (%) | P-valueb |
|---|---|---|---|---|---|---|
| 2010 | Cytokeratin 19 | P08727 | 44.1/5.04 | 14/23 | 32 | 0.0002 |
| 4008 | Cytokeratin 19 | P08727 | 44.1/5.04 | 10/17 | 22 | 0.0036 |
| 4825 | Tropomyosin 1α chain | P09493 | 32.7/4.69 | 5/13 | 15 | 0.0173 |
| 5008 | HSP27 | O14530 | 26.5/5.61 | 6/15 | 23 | 0.0004 |
| 6112 | Cytokeratin 8 | P05787 | 53.5/5.52 | 6/16 | 19 | 0.0125 |
| 3704 | Cytokeratin 8 | P05787 | 53.5/5.52 | 6/12 | 17 | 0.0081 |
| 5405 | Cytokeratin 8 | P05787 | 53.5/5.52 | 10/18 | 26 | 0.0133 |
| 2010 | Adenosylhomosysteinase | P23526 | 47.6/5.92 | 8/17 | 18 | 0.0007 |
| 4216 | Nicotinamide N-methyltransferase (NNMT) | P40261 | 29.6/5.56 | 9/22 | 42 | 0.0002 |
| 2010 | Glutathione S-transferase omega 1 | P78417 | 27.6/6.24 | 5/17 | 21 | 0.0015 |
a
A relative change (2-fold or more) in a protein highly expressed in SCC12 cells compared with one in SCC13 cells.
b
P-values were determined from the density of each pair spot obtained from PDQuest analyses of three independent experiments. MW, molecular weight; pI, protein isoelectric point.