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. 2019 Sep 16;42(5):1767–1780. doi: 10.3892/or.2019.7316

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Copyright: © Zhang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 1. — Filtering of differentially expressed miRNAs. (A) Data analysis pipeline to search for survival-correlated critically important miRNAs. (B) Volcano plot revealing a total of 46 miRNAs (red and green) that were differentially expressed between 312 NPC samples and 18 normal samples (cut-off criteria are fold change >2.5 and adjust P-value (FDR) <0.01). The red and green spots represent upregulated and downregulated miRNAs, respectively. miRNAs, microRNAs; NPC, nasopharyngeal carcinoma; DEGs, differentially expressed genes; ROC, receiver operating characteristic; WGCNA, weighted gene co-expression network analysis; PPI, protein-protein interaction; BPA; biological pathway; FDR, false discovery rate.