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. 2019 Aug 7;14(12):2118–2125. doi: 10.4103/1673-5374.262592

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Copyright: © Neural Regeneration Research

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Effect of growth arrest-specific 5 (GAS5) on levels of choline acetyltransferase (ChAT) and acetylcholine (ACh) in cells.

(A, B) ChAT protein content of the lncRNA GAS5-overexpressing lentivirus (LV-GAS5) group was significantly increased compared with other groups. (C) The LV-GAS5 group had increased ACh levels at 48 and 72 hours (h) compared with other groups, whereas, there were no differences among groups at 24 and 96 hours. Data are expressed as the mean ± SEM. ***P < 0.001, vs. control group; ###P < 0.001, vs. negative control lentivirus (LV-NC) group (one-way analysis of variance followed by independent sample t-test). The experiment was repeated three times.