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. 2019 Oct 4;13:1062. doi: 10.3389/fnins.2019.01062

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Copyright © 2019 Lee, Eun, Kim, Lee and Park.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Relationship between changes in functional connectivity and changes in LBEpain (LBEpost vs. LBEpre) after real (REAL) and phantom (PHNT) acupuncture stimulation. (A) Functional connectivity changes (mPFC–pINS in REAL, PCC–aINS, and S1_back–pINS in PHNT) associated with decreased LBEpain. Increased functional connectivities (dACC–MCC and aINS–pINS) were found in PHNT. (B) Correlation between changes in LBEpain (Y-axis) and functional connectivity (X-axis). DMN, default mode network; SMN, sensorimotor network; SN, salience network; FC, functional connectivity; LBP, low back pain; mPFC, medial prefrontal cortex; PCC, posterior cingulate cortex; S1_back, low back region in primary somatosensory cortex; dACC, dorsal anterior cingulate cortex; aMCC, anterior middle cingulate cortex; aINS, anterior insular cortex; pINS, posterior insular cortex; Y, Y-axis; X, X-axis.