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. 2019 Oct 4;10:2272. doi: 10.3389/fmicb.2019.02272

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Copyright © 2019 Qian, Zhang, Jia, Sun, Zhang, Xiao and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Fecal detoxification and humoral immune response in piglets challenged with PEDV-JS-A. (A) Fecal virus shedding in PEDV-challenged piglets. (B) Detection of PEDV IgG in serum samples from PEDV-challenged piglets. (C) PEDV IgA detection in serum samples from PEDV-challenged piglets. (D) Detection of neutralizing antibodies in serum samples of immunized piglets. (Data were analyzed as mean ± SEM) (n = 3 for the JS-A group, and statistically significant for the unchallenged group by Student’s t test. ^***p < 0.001).