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. 2019 Oct 4;10:790. doi: 10.3389/fgene.2019.00790

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Copyright © 2019 Dai, Mei, Chen and Cai

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Interactions between ANLN and KDR in different breast cancer cells. (A) KDR gene expression after downregulating ANLN in each cell line. (B) KDR gene expression after upregulating ANLN in each cell line. (C) ANLN gene expression after downregulating KDR in each cell line. (D) ANLN gene expression after upregulating ANLN in each cell line. Bars represent mean ± SD from at least three independent experiments. * represents statistical significance (p < 0.05) from Student’s t test. The red dotted line represents the expression level where no external modulation was done. SUM159 and MDAMB231 are triple negative breast cancer cells, MCF7 is a luminal breast cancer cell line, and MCF10A represents normal breast epithelial cells.