Table 2.

Recommended risk scoring systems for the assessment of ischemic and bleeding risk in patients with NSTEMI15, 68, 69, 70

	GRACE	TIMI	CRUSADE
Risk measured	Ischemic	Ischemic	Bleeding
Risk estimated	Mortality while in hospital, at 6 months, at 1 year, and at 3 years The combined risk of death or MI at 1 year	Adverse outcome (death, MI, urgent revascularization)	In‐hospital major bleeding event
Variables used to calculate score	Age, systolic blood pressure, pulse rate, serum creatinine, Killip class at presentation, cardiac arrest at admission, elevated cardiac biomarkers, and ST deviation	Age ≥65 years, ≥3 CAD risk factors, known CAD, aspirin use in the past 7 days, severe angina (≥2 episodes within 24 hours), ST change ≥0.5 mm, and positive cardiac marker	Baseline hematocrit, diabetes mellitus, GFR: Cockcroft‐Gault, heart rate on admission, prior vascular disease, sex, signs of CHF on admission, and systolic blood pressure on admission
Online calculator	https://www.mdcalc.com/grace‐acs‐risk‐mortality‐calculator	https://www.mdcalc.com/timi‐risk‐score‐ua‐nstemi	http://www.crusadebleedingscore.org/

Abbreviations: CAD, coronary artery disease; CHF, congestive heart failure; CRUSADE, Can Rapid risk stratification of Unstable angina patients Suppress ADverse outcomes with Early implementation of the ACC/AHA guidelines; GFR, glomerular filtration rate; GRACE, Global Registry of Acute Coronary Events; MI, myocardial infarction; NSTEMI, non‐ST‐segment elevation myocardial infarction; TIMI, Thrombolysis In Myocardial Infarction.