Table 1.
Clinical characteristics of patients with and without elevated hs‐cTnT
| Variable | hs‐cTnT >14 ng/L (n = 65) | hs‐cTnT ≤14 ng/L (n = 176) | P‐value |
|---|---|---|---|
| Age, years, mean (SD) | 71.0 (10.7) | 62.5 (9.5) | <.001 |
| Male sex, n (%) | 49 (75.4) | 130 (73.9) | .811 |
| ODT, minutes, mean (SD) | 118.7 (61.7) | 109.1 (56.1) | .253 |
| DNT, minutes, mean (SD) | 66.9 (25.7) | 65.0 (27.6) | .620 |
| ONT, minutes, mean (SD) | 185.7 (61.0) | 174.7 (57.3) | .198 |
| NIHSS on admission, median (IQR) | 5.0 (2.0‐10.5) | 3.0 (2.0‐6.0) | .010 |
| History | |||
| Smoking, n (%) | 28 (43.1) | 94 (53.4) | .155 |
| Alcohol abuse, n (%) | 20 (30.8) | 62 (35.2) | .517 |
| Hypertension, n (%) | 48 (73.8) | 115 (65.3) | .210 |
| Hyperlipidemia, n (%) | 33 (50.8) | 87 (49.4) | .854 |
| Diabetes mellitus, n (%) | 25 (38.5) | 40 (22.7) | .015 |
| Coronary artery disease, n (%) | 25 (38.5) | 38 (21.6) | .008 |
| Previous MI history, n (%) | 7 (10.8) | 9 (5.1) | .118 |
| Atrial fibrillation, n (%) | 16 (24.6) | 16 (9.1) | .002 |
| Congestive heart failure, n (%) | 8 (12.3) | 11 (6.3) | .121 |
| Previous stroke, n (%) | 17 (26.2) | 44 (25.0) | .855 |
| Chronic obstructive pulmonary disease, n (%) | 0 (0.0) | 2 (1.1) | .388 |
| Epilepsy, n (%) | 1 (1.5) | 2 (1.1) | 1.000 |
| Creatinine, μmol/L, mean (SD) | 81.2 (31.2) | 71.9 (20.3) | .008 |
| eGFR (mL/min/1.73 m2), mean (SD) | 81.5 (22.1) | 94.5 (19.7) | <.001 |
| Glucose (mmol/L), mean (SD) | 8.8 (3.7) | 7.9 (3.3) | .092 |
| Insular cortex involvement, n (%) | 17 (26.2) | 21 (11.9) | .007 |
| Right insula involvement, n (%) | 8 (47.1) | 15 (71.4) | .127 |
| Stroke etiology (TOAST) | .001 | ||
| Cardioembolic, n (%) | 36 (55.4) | 72 (40.9) | |
| Small‐vessel disease, n (%) | 11 (16.9) | 9 (5.1) | |
| Large‐artery arteriosclerosis, n (%) | 13 (20.0) | 75 (42.6) | |
| Undefined, n (%) | 5 (7.7) | 18 (10.2) | |
| Other defined, n (%) | 0 (0.0) | 2 (1.1) | |
Abbreviations: eGFR, estimated glomerular filtration rate; hs‐cTnT, high‐sensitivity cardiac troponin T; IQR, interquartile range; MI, myocardial infarction; NIHSS, National Institutes of Health Stroke Scale; ODT, onset‐to‐door time; DNT, door‐to‐needle time; ONT, onset‐to‐needle time.