Table 3. Ongoing immunotherapy trials for patients with TETs.
Intervention | Tumor type | Clinical trial ID | Primary objective |
---|---|---|---|
Avelumab | Thymic carcinoma, Thymoma | NCT03076554 | Safety and response rate |
Nivolumab | Thymic carcinoma, B3 thymoma | NCT03134118 | Six-month PFS |
Pembrolizumab | Thymic carcinoma, Thymoma | NCT03295227 | Dose limiting toxicity |
Pembrolizumab and Sunitinib | Thymic carcinoma | NCT03463460 | Response rate |
Pembrolizumab and Epacadostat | Thymic carcinoma | NCT02364076 | Response rate |
TET, thymic epithelial tumor; PFS, progression-free survival.