Table 2. PET data and univariate analysis.
Mean (+/- Standard Deviation) | Median | Range | PFS | OS | |
---|---|---|---|---|---|
PET1 | |||||
SUVmax1 | 16 (+/-8) | 14 | 4–50 | p = 0.52 | p = 0.79 |
SUVmean1 | 8 (+/-5) | 7 | 2–31 | p = 0.39 | p = 0.54 |
SUVpeak1 | 14 (+/-7) | 11 | 3–47 | p = 0.53 | p = 0.79 |
MTV1 | 73 (+/-65) | 54 | 5–333 | p = 0.0004 | p = 0.75 |
TLG1 | 613 (+/-643) | 399 | 28–3216 | p = 0.02 | p = 0.55 |
PET2 | |||||
SUVmax2 | 9 (+/-9) | 8 | 2–50 | p = 0.31 | p = 0.004 |
SUVmean2 | 5 (+/-5) | 3 | 1–31 | p = 0.46 | p = 0.01 |
SUVpeak2 | 7 (+/-8) | 6 | 0–47 | p = 0.28 | p = 0.001 |
MTV2 | 30 (+/- 28) | 22 | 2–140 | p = 0.056 | p = 0.03 |
TLG2 | 160 (+/- 294) | 75 | 3–1967 | p = 0.02 | p< 0.001 |
Response | |||||
ΔSUVmax | -40% (+/- 31%) | -43% | -93%−+26% | p = 0.41 | p< 0.001 |
ΔSUVmean | -43% (+/-30%) | -48% | -93%−+18% | p = 0.87 | p = 0.04 |
ΔSUVpeak | -45% (+/- 31%) | -48% | -100%−+19% | p = 0.27 | p< 0.001 |
ΔMTV | -45% (+/- 48%) | -54% | -94%−+164% | p = 0.85 | p = 0.052 |
ΔTLG | -67% (+/- 36%) | -76% | -99%−+106% | p = 0.36 | p = 0.001 |
Δ Σ lesion diameters | -28% (+/-22%) | -26% | -72%−+37% | p = 0.08 | p = 0.07 |