. Author manuscript; available in PMC: 2019 Oct 11.

Published in final edited form as: Infect Control Hosp Epidemiol. 2008 Sep;29(9):842–846. doi: 10.1086/590261

TABLE 2.

Characteristics of the Best-Performing Algorithms for the Surveillance of Central Line–Associated Bloodstream Infection (CLABSI), Compared With Manual Surveillance, and the Screening of 771 Isolates Recovered From 540 Patients at Barnes-Jewish Hospital

Algorithm	No. (%) of isolates

	Classified as representing CLABSI	Not classified as representing CLABSI	Comparison with manual surveillance

			Sens, %	Spec, %	PPV, %	NPV, %

1. Nosocomial + CVC	459 (60)	312 (40)	97.1	44.2	14.8	99.4
2. Nosocomial + CVC + [Non-CSC or (CSC + Fever)]	415 (54)	356 (46)	95.7	50.4	16.1	99.2
3. Nosocomial + CVC + [Non-CSC or (CSC + Vanc)]	339 (44)	432 (56)	92.9	60.9	19.2	98.8
4. Nosocomial + CVC + [Non-CSC or (CSC + Repeat ( + ))]	290 (38)	481(62)	94.3	68.0	22.8	99.2
5. Nosocomial + CVC + {Non-CSC or [CSC + (Vanc or Repeat ( + ))]}	362 (47)	409 (53)	95.7	57.9	18.5	99.3
6. Nosocomial + CVC + {Non-CSC or [CSC + Fever + (Vanc or Repeat ( + ))]}	331 (43)	440 (57)	94.3	62.2	19.9	99.1

NOTE. See Table 1 for descriptions of the algorithms. CSC, common skin contaminant; CVC, central-venous catheter; NPV, negative predictive value; PPV, positive predictive value; Repeat (+), another positive-culture result; Sens, sensitivity; Spec, specificity; Vanc, vancomycin.