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. Author manuscript; available in PMC: 2019 Oct 11.
Published in final edited form as: Obesity (Silver Spring). 2019 Apr 1;27(5):803–812. doi: 10.1002/oby.22440

Figure 4.

Figure 4.

Circulating endocrine hormones. (A) BD significantly increased circulating GLP-1. WT-BD vs. WT-LFD and WT-HFD, p < 0.0001; FXRko-HFD vs. FXRko-BD, p < 0.05, and WT-BD vs. FXRko-BD, p < 0.05. (B) HFD enhanced circulating leptin levels in HFD-fed WT mice, but not in HFD-fed FXRko mice. WT-LFD vs. WT-HFD, p < 0.01; and WT-HFD vs. WT-BD, p < 0.05. (C) BD decreased circulating resistin in both HFD-fed WT and FXRko mice, but not statistically significant (p > 0.05). (D) to (F), there were no statistical differences among groups (p > 0.05). N = 5 per group.