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. Author manuscript; available in PMC: 2020 Oct 9.
Published in final edited form as: Circ Arrhythm Electrophysiol. 2019 Oct 9;12(10):e005557. doi: 10.1161/CIRCEP.117.005557

Figure 2: Effect of ranolazine on singularity point (SP) density in stretch-induced paroxysmal AF on the LA epicardium from perfused hearts.

Figure 2:

(A) Time course of SP density during paroxysmal AF. At time=0 mins (dashed line) 10 μM ranolazine is added to the perfusate. (B) Average SP density was decreased (*p<0.001, N=8) during ranolazine perfusion. (C) Representative phase maps of the LA epicardium before (left) and during (right) perfusion of ranolazine show multiple rotors (white arrows indicate direction of rotation around SP).