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. Author manuscript; available in PMC: 2020 Oct 9.
Published in final edited form as: Circ Arrhythm Electrophysiol. 2019 Oct 9;12(10):e005557. doi: 10.1161/CIRCEP.117.005557

Figure 5: Effect of ranolazine on singularity point (SP) density in tachypacing-induced persistent AF on the LA epicardium from perfused hearts.

Figure 5:

(A) Time course of SP density during persistent AF in 9 sheep hearts. Continuous ranolazine (10 μM) perfusion begins at time 0 (dashed line). (B) Average SP density was not changed before and during perfusion of ranolazine. (C) Representative phase maps of the LA epicardium before (left) and during (right) perfusion of ranolazine show multiple rotors (white arrows indicate direction of rotation around SP).