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. Author manuscript; available in PMC: 2019 Nov 17.
Published in final edited form as: Lab Invest. 2019 May 17;99(10):1547–1560. doi: 10.1038/s41374-019-0264-3

Figure 9.

Figure 9

Progression of diabetic retinopathy in the Nile rat. In our cohort, 75% of diabetic rats ≥ 24 weeks old had increased acellular capillaries, mean RBG ≥ 128 mg/dL; duration of diabetes ≥ 8 weeks; 17% of diabetic rats ≥ 32 weeks old had lipemia retinalis, mean RBG ≥ 235 mg/dL; duration of diabetes ≥ 24 weeks, 23% of diabetic rats ≥ 45 weeks old had microvascular abnormalities, mean RBG ≥ 277 mg/dL, duration of diabetes ≥ 32 weeks; 3% of diabetic rats ≥ 52 weeks old had localized extensive capillary loss, mean RBG ≥ 237 mg/dL, duration of diabetes ≥ 30 weeks; 7% of diabetic rats ≥ 68 weeks old had proliferative diabetic retinopathy, mean RBG ≥ 448 mg/dL, duration of diabetes ≥ 48 weeks.