Figure 1.
Single nucleotide polymorphisms identified in the IL-17 signalling pathway that have been linked to axial spondyloarthritis and psoriatic arthritis. aSignificant association shown in European but not Asian populations204; bNo risk associated with this SNP shown in certain studies204–206; cNo risk associated with this SNP shown in certain studies207; dSNP can be associated with risk or protection depending on the specific mutation. AS, ankylosing spondylitis; IL-1R2, interleukin 1 receptor; IL-6R, interleukin 6 receptor; IL17R, interleukin receptors; PsA, psoriatic arthritis; SNP, single nucleotide polymorphism.
