Table 3.

Final regression model for disease worsening

	p Value	OR	95% CI
Age (years)	0.001	1.02	1.01 to 1.04
Lung fibrosis	0.0004	2.21	1.43 to 3.41
CRP elevation	0.002	1.80	1.23 to 2.63
Muscle weakness	0.015	1.64	1.10 to 2.45
Active DU	0.026	1.64	1.06 to 2.54
Proteinuria	0.064	1.75	0.97 to 3.16
Pericardial effusion	0.098	1.65	0.91 to 2.97
Significant dyspnoea	0.491	1.20	0.72 to 2.00

Parameters in bold had strong evidence for a significant association with disease progression in the final model.

CRP, C-reactive protein; DU, digital ulcer.