The initial NCI funding and additional funding leveraged by funding to four Alliance CCNEs, which have been funded for all Phases of the program (California Institute of Technology, Northwestern University, Stanford University, and University of North Carolina at Chapel Hill). The graph represents the cumulative investment by NCI to these four CCNEs (gray solid line), the cumulative funds leveraged by these CCNEs from other public funding sources (blue solid line), and the cumulative total of both funds leveraged, and equity invested by companies that commercialized CCNE technologies (black solid line). For additional comparison, the cumulative investment by the NCI to all funded Alliance CCNEs, over all Phases, is also displayed (gray dashed line).