. Author manuscript; available in PMC: 2020 Nov 1.

Published in final edited form as: Am J Reprod Immunol. 2019 Sep 3;82(5):e13171. doi: 10.1111/aji.13171

Table 1.

Clinical and demographic characteristics of women who underwent spontaneous preterm labor

	Preterm labor and birth with intra-amniotic infection (n=10)	Preterm labor and birth with intra-amniotic inflammation (n=16)	p-value
Maternal age (years; median [IQR])^a	27.5 (22.8–35.8)	25.5 (22–28.3)	0.3
Body mass index (kg/m²; median [IQR])^a	28.3 (27–36.5)^d	26.3 (24.2–30.7)	0.1
Primiparity^b	0% (0/10)	12.5% (2/16)	0.5
Race^b			1
African-American	80% (8/10)	81.3% (13/16)
Caucasian	20% (2/10)	12.5% (2/16)
Other	0% (0/10)	6.3% (1/16)
Gestational age at amniocentesis (weeks; median [IQR])^a	25.9 (22.5–29.8)	27 (22.9–31.2)	0.4
IL-6 (ng/mL; median [IQR])^a	128.7 (78–186.2)	47.8 (16.7–122.9)	0.04
White blood cell count, cells/mm³,^a	307 (89–1254.5)	2 (0–11.8)	0.003
Amniotic fluid glucose, mg/dL^a	3.5 (1–9.8)	12.5 (6–26)	0.053
Gestational age at delivery (weeks; median [IQR])^a	25.9 (23–30)	27.6 (23.4–31.3)	0.4
Cesarean section^b	0% (0/10)	31.3% (5/16)	0.1
Birthweight (grams)^a	935 (533.3–1428.8)	1037.5 (697.5–1778.8)	0.6
Acute maternal inflammatory response
Stage 1 (acute subchorionitis)^b	0% (0/8)^c	23.1% (3/13)^d	0.2
Stage 2 (acute chorioamnionitis)^b	37.5% (3/8)^c	30.8% (4/13)^d	1
Stage 3 (acute necrotizing chorioamnionitis)^b	50% (4/8)^c	30.8% (4/13)^d	0.6
Acute fetal inflammatory response
Stage 1 (acute phlebitis/chronic vasculitis)^b	50% (4/8)^c	53.8% (7/13)^d	1
Stage 2 (acute arteritis)^b	25% (2/8)^c	0% (0/13)^d	0.1
Stage 3 (necrotizing funisitis)^b	12.5% (1/8)^c	0% (0/13)^d	0.3

Data are given as median (interquartile range, IQR) and percentage (n/N).

Mann-Whitney U-test.

Fisher’s exact test.

Two missing data.

Three missing data.