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. Author manuscript; available in PMC: 2020 Nov 1.
Published in final edited form as: Biol Psychiatry. 2019 May 13;86(9):682–692. doi: 10.1016/j.biopsych.2019.04.035

Figure 6.

Figure 6.

Development-dependent changes in NMDA receptor transmission in PVINs and SSTINs in the IL-mPFC. A) NMDA receptor-mediated currents in the PVINs of pre-adolescent (13 neurons/3 mice), adolescent (10 neurons/3 mice), and adult mice (14 neurons/3 mice) (F (2, 32) = 3.8, p = 0.033; pre-adolescent vs adolescent: p = 0.075; pre-adolescent vs adult: p = 0.043; adolescent vs adult: p = 0.99). Left panel show example traces. Scale: 50 ms/20 pA. B) NMDA receptor-mediated currents in the SSTINs of pre-adolescent (10 neurons/5 mice), adolescent (10 neurons/5 mice), and adult mice (13 neurons/6 mice) (F (2, 30) = 5.8, p = 0.007; pre-adolescent vs adolescent: p = 1; pre-adolescent vs adult: p = 0.013; adolescent vs adult: p = 0.033). Left panel show example traces. Scale: 50 ms/20 pA.