Table 1.

Predictors of undergoing intrahepatic cholangiocarcinoma resection at an academic (versus community) facility, based on univariate and multivariable analysis.

Characteristic	Community Center (n=423)	Academic Center (n=1,833)	Unadjusted P-value	Odds Ratio (95% CI)	Adjusted P-value
Age ≥65 years old	253 (59.8%)	859 (46.9%)	<0.001	0.78 (0.56-1.09)	0.14
Male sex	180 (42.6%)	866 (47.2%)	0.08	1.21 (0.94-1.55)	0.14
Race			0.12
White	360 (86.1%)	1,468 (82.0%)		Reference
Black	16 (3.8%)	121 (6.8%)		2.34 (1.28-4.29)	0.01
Hispanic	22 (5.3%)	108 (6.0%)		1.58 (0.92-2.71)	0.10
Asian	20 (4.8%)	93 (5.2%)		1.28 (0.74-2.20)	0.37
Charlson/Deyo score			<0.001
CDCC 0	247 (58.4%)	1,269 (69.2%)		Reference
CDCC 1	108 (25.5%)	404 (22.0%)		0.74 (0.55-0.99)	0.04
CDCC ≥2	68 (16.1%)	160 (8.7%)		0.45 (0.31-0.65)	<0.001
Insurance status			<0.001
Private	147 (35.2%)	776 (44.0%)		Reference
Medicaid	10 (2.4%)	88 (5.0%)		1.87 (0.86-4.09)	0.12
Medicare	247 (59.1%)	835 (47.4%)		0.81 (0.58-1.15)	0.24
None or other government	14 (3.4%)	64 (3.6%)		0.82 (0.41-1.67)	0.59
Distance between patient zip code and hospital			<0.001
<10 miles	166 (39.2%)	392 (21.4%)		Reference
10-40 miles	154 (36.4%)	640 (34.9%)		1.97 (1.47-2.65)	<0.001
>40 miles	103 (24.4%)	801 (43.7%)		3.77 (2.73-5.21)	<0.001
Clinical stage			0.37
Stage 1	157 (37.2%)	609 (33.3%)		Reference
Stage 2	81 (19.2%)	344 (18.8%)		0.94 (0.67-1.33)	0.74
Stage 3	40 (9.5%)	178 (9.7%)		1.02 (0.64-1.62)	0.93
Unknown	144 (34.1%)	700 (38.2%)		1.34 (1.00-1.81)	0.051
Tumor size			0.13
<3 cm	67 (17.1%)	360 (20.9%)		Reference
3-5 cm	129 (32.9%)	498 (28.9%)		0.84 (0.59-1.22)	0.36
>5 cm	196 (50.0%)	866 (50.2%)		0.86 (0.61-1.21)	0.38
Tumor grade			0.44
Well differentiated	54 (14.6%)	198 (12.5%)		Reference
Moderately differentiated	208 (56.4%)	894 (56.2%)		1.32 (0.91-1.93)	0.14
Poorly differentiated or undifferentiated	107 (29.0%)	499 (31.4%)		1.25 (0.83-1.89)	0.28

CI, confidence interval; CDCC, Charlson/Deyo Comorbidity Score