Table 2.

Urine AOG/ creatinine ratio (ng/mg) and AER (mg/24 hr) in the DCCT and EDIC study visits prior to outcome.

	Cases N = 34	Controls N = 51	P‐value*
DCCT visit. AOG/Creatinine Ratio (ng/mg) (Median and range)	2.75 (0.38–30)	3.16 (0.53–26)	0.67
EDIC visit. AOG/Creatinine ratio (ng/mg) (Median and range)	13.9 (0.96–989)	3.83 (0.44–228)	0.003
DCCT visit. AER (mg/24hr) (Median and range)	10.0 (1.4–99.7)	10.1 (4–46)	0.61
EDIC visit. AER (mg/24hr) (Median and range)	86 (4.3–7357)	9 (3–20)	0.01

Urine AOG/ creatinine (ng/mg) was measured prior to outcome (eGFR <60 mL/min per 1.73m^2.) in DCCT visit (range 17‐20 years prior to outcome) and in EDIC visit (range 1–7 years prior to outcome).

^*Reflects the P‐value obtained as per conditional regression analysis.