Table 2.
Summary of raw numbers of Tom+, Fos+, and Tom+/Fos+ neurons in home caged WT mice, and in WT and EphB2−/− mutant mice subjected to fear conditioning
| Cell types | Home-cage WT (mean ± SEM) | WT (mean ± SEM) | EphB2 −/− (mean ± SEM) | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Brain regions | Tom+ | Fos+ | Tom+/Fos+ | Tom+ | Fos+ | Tom+/Fos+ | Tom+ | Fos+ | Tom+/Fos+ |
| DG-upper blade | 4.4 ± 0.43 | 9.5 ± 0.43 | 0.07 ± 0.04 | 5.76 ± 0.43 | 16.34 ± 0.6 | 0.09 ± 0.04 | 6.08 ± 0.58 | 15.25 ± 2.07 | 0.042 ± 0.04 |
| DG-lower blade | 2.63 ± 0.35 | 7.73 ± 0.68 | 0 ± 0 | 2.92 ± 0.27 | 9.49 ± 0.59 | 0 ± 0 | 2.46 ± 0.45 | 7.21 ± 1.21 | 0 ± 0 |
| CA3 | 1.07 ± 0.36 | 20.1 ± 0.98 | 0.23 ± 0.11 | 0.78 ± 0.13 | 27.2 ± 1.03 | 0.09 ± 0.03 | 1.25 ± 0.27 | 25.04 ± 4.15 | 0.08 ± 0.08 |
| CA1 | 0.98 ± 0.16 | 7.26 ± 0.54 | 0.07 ± 0.03 | 1.17 ± 0.12 | 17.19 ± 0.8 | 0.09 ± 0.02 | 1.28 ± 0.17 | 12.67 ± 0.82 | 0.17 ± 0.04 |
| Auditory cortex | 47.61 ± 3.21 | 18.76 ± 1.97 | 3.33 ± 0.64 | 62.2 ± 2.01 | 105.15 ± 7.74 | 16.13 ± 1.18 | 62.4 ± 2.37 | 74 ± 9.65 | 13.22 ± 1.42 |
| Cortical Amygdala | 52.63 ± 5.47 | 21.97 ± 0.89 | 5.4 ± 0.39 | 46.62 ± 4.31 | 68.09 ± 6.08 | 11.96 ± 1.28 | 51.12 ± 10.91 | 53 ± 4.25 | 9.17 ± 1.79 |
| Central Amygdala | 26.23 ± 2.61 | 11.4 ± 1.61 | 1.23 ± 0.3 | 33.79 ± 3.03 | 18.20 ± 1.15 | 1.24 ± 0.16 | 33.96 ± 6.4 | 19.42 ± 3.7 | 1.71 ± 0.57 |
| BLA | 2.63 ± 0.43 | 17.5 ± 1.3 | 0.17 ± 0.1 | 3.7 ± 0.35 | 43.14 ± 2.04 | 0.74 ± 0.12 | 4.08 ± 0.58 | 37.42 ± 4.02 | 0.62 ± 0.19 |