Fig. 1.

The DDD RT call set. a–e Histograms of the total number of variants per individual for the four classes of RT events identified in the DDD cohort (Alu: blue; L1: green; SVA: orange; PPGs: red; combined RT events: grey) in size one bins. f Allele frequency distributions for the RT classes depicted in a–e in log₁₀ allele frequency bins. g Insert size estimates provided by MELT for the MEI classes ascertained in this study in log₁₀ insert size bins. All plots only include variants from unaffected parents