Fig. 4.

TF-based plasma resolution limits and early cancer detection. a Comparisons of accessibilities for selected TFs in subsamples of the COAD cohort based on their tumor fraction. Boxplots are defined as follows: centerline represents the median, the box represents the interquartile range (IQR), and the whiskers denote the first quartile –1.5 IQR and the third quartile +1.5 IQR, respectively. b Logistic regression with all 504 TFs for samples from the colon cancer cohort with stage I (left panel) and stage II (right panel), respectively. All presented results are cross-validated test-set values