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. 2019 Oct 11;9:14696. doi: 10.1038/s41598-019-50635-w

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Top three discriminative features for VRC01 and 8ANC195 classifier. (A) The top three discriminant features of the bNAb VRC01 classifier are listed in the table and highlighted on the prefusion-closed Env trimer structure in complex with VRC01 antibody (PDB ID: 5FYJ). (B) The top three discriminant features of the bNAb 8ANC195 classifier are listed in the table and highlighted in the Env trimer structure in complex with 8ANC195 bNAb, with glycans 234 and 276 depicted as green sticks (PDB ID: 5CJX).