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. 2019 Oct 11;2:375. doi: 10.1038/s42003-019-0601-5

Fig. 3.

Fig. 3

Snap29 mutant mice show signs of hyperkeratosis. Hematoxylin and eosin staining (a–c) and TEM (d–g) of dorsal skin. The stratum corneum (SC) in Snap29−/− mice was found thicker and more condensed (c, e, red arrow) than that of the Snap29+/+ or Snap29+/ mice. Abnormal structures were seen in the extracellular spaces between granulocytes and lower corneocytes. Scale bars represent 25 µm (a–c), 2 µm (d, e), and 500 nm (f, g)