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. 2019 Oct 11;2:375. doi: 10.1038/s42003-019-0601-5

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — Snap29 mutant male mice exhibit fewer gait defects as measured by Catwalk. Catwalk assay was used to monitor gait parameters in Snap29^+/+, Snap29^+/⁻, and Snap29^−/− males. The kinetic parameter swing speed was decreased on the left side of Snap29^−/− males (a). The interlimb coordination parameter support on two paws was significantly reduced in Snap29^−/− males (b). The grip strength was assessed for fore limbs (c) and hind limbs (d). Snap29^−/− males exhibited weaker fore and hind limbs than Snap29^+/+ animals. RF right front paw; RH right hind paw; LF left front paw; and LH left hind paw. RF and LF are in black and RH and LH are in gray. Statistical significance: *p < 0.05, **p < 0.01, and ***p < 0.001. Error bars represent Standard error of the Mean