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. 2019 Oct 11;2:375. doi: 10.1038/s42003-019-0601-5

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 7 — Analysis of ophthalmological defects in Snap29^−/− mice. Representative scotopic (a–c; amplitude (in microvolt) and time (in millisecond) calibrations at the left of tracing a) and photopic (d–f; amplitude (in microvolt) and time (in millisecond) calibrations at the left of tracing d) ERG wave forms. a Scotopic ERG recorded from wild-type mouse; b Scotopic ERG recorded from heterozygous mouse; c Scotopic ERG recorded from homozygous mouse with low b wave amplitude; d photopic ERG recorded from wild-type mouse; e photopic ERG recorded from heterozygous mouse; f photopic ERG recorded from homozygous mouse with low b wave amplitude. In tracings a and d, the ERG a- and b-waves are identified with letters a and b, respectively. Representative eye histology of wild-type male mouse (g) at P118; heterozygous female at P83 (h) and homozygous female mouse at P87(i). ISL inner segment layer, ONL outer nuclear layer, OPL outer plexiform layer, INL inner nuclear layer. Scale bar represents 25 µm