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. 2019 Oct 11;9:14702. doi: 10.1038/s41598-019-50976-6

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Liver inflammation is lower in CD40^fl/flCD11c^cre compared to WT mice on a NASH inducing diet. (A) Mean histopathological inflammation grade. (B) quantification of Mac3 staining in the liver (C) quantification of CD3 staining in the liver. (D) Liver leukocyte subsets analyzed by FACS. (E) plasma ALT levels. (F) plasma AST levels. Data is represented as mean ± SEM. *P < 0.05 for comparison between WT and CD40^fl/flCD11c^cre mice fed a similar diet. n = 6/group for CD, and n = 15/group for NASH diet.