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. 2019 Oct 11;9:14695. doi: 10.1038/s41598-019-51193-x

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Effect of metformin pretreatment on the effectiveness of P. chabaudi infection in mice. Percentage parasitemia assessed through evaluation of blood smears every day until the 5th day after infection. Closed triangles represent controls (n = 9), closed circles represent metformin pretreated controls (n = 9), open triangles represent the infected group (n = 9), and open circles represent the infected group pretreated with metformin (n = 7). Statistical analysis: two-way ANOVA followed by Tukey’s multiple comparisons test. Values are presented as mean ± standard error. ^***p < 0.001.