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The main pathways activated by different estrogen receptor isoforms in breast cancer stem cells, responsible for cell proliferation and tamoxifen-resistance. GPER: G-protein coupled receptor; ERα36: estrogen receptor alpha 36; ERβ: estrogen receptor beta; MEK: Mitogen activated protein kinase; ERK: extracellular signal-regulated kinase; YAP: Yes-associated protein; TAZ: Tafazzin.
