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. 2019 Sep 15;11(9):6232–6248.

Figure 8.

Figure 8

Cellular expressions of DNA-damaged biomarkers by day 14 after ICH procedure. A-D. Illustrating immunofluorescent (IF) microscopy (400 ×) for identification of positively-stained γ-H2AX cells (pink color). E. Analytic result of number of γ-H2AX+ cells, * vs. other groups with different symbols (†, ‡, §), P<0.0001. F-I. Illustrating IF microscopy (400 ×) for identification of positively-stained 53BP1 cells (green color). J. Analytic result of number of 53BP1+ cells, * vs. other groups with different symbols (†, ‡, §), P<0.0001. Scale bars in right lower corner represent 20 µm. All statistical analyses were performed by one-way ANOVA, followed by Bonferroni multiple comparison post hoc test (n=6 for each group). Symbols (*, †, ‡, §) indicate significance (at 0.05 level). SC = sham-operated control; ICH = intracranial hemorrhage; HA = hyaluronic acid; iPSC-MSC = induced pluripotent stem cell-derived mesenchymal stem cell.