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Nrg4 may attenuate renal dysfunction via TNF-R1 signaling instead of TNF-R2 signaling. The levels of TNF-R1, TNR-R2, TRADD were detected by Western blot analysis. The columns and error bars represent the mean and SEM. ***P < 0.001, vs. Control group. #P < 0.05, ###P < 0.001, vs. STZ group.
