Table 2.
Association between CD204+ cell number and clinicopathological factors
| Clinical parameters | CD204+ cell number/HPF (Mean ± SD) | t/χ2 or F Value | P |
|---|---|---|---|
| Gender | 2.229 | 0.027 | |
| Male | 37.58±18.10 | ||
| Female | 43.57±19.19 | ||
| Location | 0.006 | 0.994 | |
| Proximal | 38.99±20.09 | ||
| Middle | 39.33±18.54 | ||
| Distal | 39.42±18.22 | ||
| Size | 2.235 | 0.026 | |
| ≥5 cm | 42.54±19.32 | ||
| <5 cm | 37.00±17.75 | ||
| Histology type | 0.475 | 0.700 | |
| Papillary adenocarcinoma | 40.80±19.14 | ||
| Tubular adenocarcinoma | 40.20±19.16 | ||
| Mucinous adenocarcinoma | 35.78±21.42 | ||
| Signet-ring cell carcinoma | 37.51±16.25 | ||
| Lauren classification | 1.581 | 0.208 | |
| Diffuse type | 41.76±19.60 | ||
| Intestinal type | 37.32±17.54 | ||
| Mixed type | 38.88±19.84 | ||
| Differentiation | 1.021 | 0.362 | |
| Well | 32.33±7.86 | ||
| Moderately | 37.88±17.96 | ||
| Poorly | 40.38±19.22 | ||
| Invasion Depth (T Grade) | 7.786 | 0.000 | |
| T1 | 36.43±14.20 | ||
| T2 | 36.03±17.84 | ||
| T3 | 39.88±20.59 | ||
| T4 | 59.11±19.20 | ||
| Lymphatic Metastasis (N Grade) | 3.013 | 0.003 | |
| N0 | 35.47±14.62 | ||
| N1 | 42.59±20.89 | ||
| Distant Metastasis (M Grade) | 4.945 | 0.000 | |
| M0 | 37.10±17.37 | ||
| M1 | 54.49±19.81 | ||
| TNM Stages | 8.790 | 0.000 | |
| I | 35.22±14.08 | ||
| II | 36.61±18.38 | ||
| III | 38.84±19.69 | ||
| IV | 54.49±19.80 | ||
| Lymphatic invasion | 2.004 | 0.047 | |
| Yes | 42.11±21.14 | ||
| No | 37.04±15.94 | ||
| Vascular invasion | 1.892 | 0.060 | |
| No | 37.07±15.54 | ||
| Yes | 41.76±21.22 | ||
| COX2 Expression | 8.483 | 0.000 | |
| Positive | 46.95±17.77 | ||
| Negative | 28.99±14.18 |
All cases were classified according to the World Health Organization’s (2010) pathological classification of gastric cancer. Invasion Depth (T Grade) grade T1 includes T1a and T1b, and T4 includes T4a and T4b. Lymphatic Metastasis (N Grade) grade N3 includes N3a and N3b. TNM grade I includes Ia and Ib, TNM grade II includes IIa and IIb, and TNM grade III includes IIIa, IIIb and IIIc.