Table 1. Composition of most common preservation solutions for liver transplantation.
Solution component or characteristic | Blood | UW | HTK | IGL-1 | SCOT 15 | Celsior |
---|---|---|---|---|---|---|
Sodium ion (mmol/L) | 140 | 30 | 15 | 120 | 118 | 100 |
Potassium ion (mmol/L) | 5 | 125 | 9 | 25 | 5 | 15 |
Magnesium ion (mmol/L) | 0.8 | 5 | 4 | 5 | 1.2 | 13 |
Calcium ion (mmol/L) | 2.5 | 0.015 | 1.75 | 0.25 | ||
Chloride ion (mmol/L) | 104 | |||||
Sulphate ion (mmol/L) | 1.4 | 5 | ||||
Phosphate (mmol/L) | 3.2 | 25 | ||||
Bicarbonate (mmol/L) | 25 | 25 | ||||
Glucose (mmol/L) | 7 | 11 | ||||
Raffinose (mmol/L) | 30 | 30 | ||||
Lactobionate (mmol/L) | 100 | 100 | 80 | |||
Adenosine (mmol/L) | 5 | 5 | ||||
Histidine (mmol/L) | 180 | 30 | ||||
Histidine · HCI · H2O (mmol/L) | 18 | |||||
Potassium hydrogen 2-ketoglutarate (mmol/L) | 1 | |||||
Mannitol (mmol/L) | 30 | 60 | ||||
Glutathione (mmol/L) | 4 | 3 | 3 | |||
Allopurinol (mmol/L) | 1 | 1 | ||||
Tryptophan (mmol/L) | 2 | |||||
HES (g/L) | 50 | |||||
PEG 20KDa (g/L) | 15 | |||||
PEG 35KDa (g/L) | 1 | |||||
pH | 7.4 | 7.3 | 7.4 | 7.4 | 7.3 | 7.4 |
Viscosity (centistokes) | 1.6 | 2.4 | 1.8 | 1.28 | 1.6 | 1.15 |
Osmolarity (mOsm) | 308 | 320 | 310 | 290 | 320 | 320 |
UW, University of Wisconsin; HTK, Histidine-Tryptophan-Ketoglutarate; IGL-1, Institut George Lopez-1; SCOT 15, Solution pour la Conservations des Organes pour la Transplantation-15; HES, hydroxyethyl starch; PEG, polyethylene glycol.